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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA1B
All Species:
30
Human Site:
T234
Identified Species:
66
UniProt:
P35368
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35368
NP_000670.1
520
56836
T234
Y
I
V
A
K
R
T
T
K
N
L
E
A
G
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q28524
418
44639
Q176
S
F
A
P
I
M
S
Q
W
W
R
V
G
A
D
Dog
Lupus familis
XP_536449
618
67286
T234
Y
I
V
A
K
R
T
T
K
N
L
E
A
G
V
Cat
Felis silvestris
Mouse
Mus musculus
P97717
514
56400
T233
Y
I
V
A
K
R
T
T
K
N
L
E
A
G
V
Rat
Rattus norvegicus
P15823
515
56567
T234
Y
I
V
A
K
R
T
T
K
N
L
E
A
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506393
511
56733
T236
Y
V
V
A
K
K
T
T
K
N
L
E
A
G
V
Chicken
Gallus gallus
XP_414483
507
56995
T238
Y
I
V
A
K
R
T
T
K
N
L
E
A
G
V
Frog
Xenopus laevis
O42574
385
43291
Y143
A
I
T
S
P
F
R
Y
Q
S
L
L
T
K
G
Zebra Danio
Brachydanio rerio
XP_001922013
544
60273
T231
Y
I
V
A
K
R
T
T
K
N
L
E
A
G
V
Tiger Blowfish
Takifugu rubipres
O42385
423
46982
M181
F
S
I
S
I
P
P
M
L
G
W
R
S
A
E
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203873
574
63580
Y230
Y
Q
T
V
S
V
E
Y
K
S
R
H
G
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
32.1
76.8
N.A.
94.8
94.6
N.A.
77.6
70.9
28
54
25.9
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
N.A.
46.7
79.1
N.A.
96.3
96.5
N.A.
82.8
78.8
43.4
64.3
42.6
N.A.
N.A.
N.A.
49.6
P-Site Identity:
100
N.A.
0
100
N.A.
100
100
N.A.
86.6
100
13.3
100
0
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
N.A.
6.6
100
N.A.
100
100
N.A.
100
100
33.3
100
26.6
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
64
0
0
0
0
0
0
0
0
64
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
64
0
0
10
% E
% Phe:
10
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
19
73
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
64
10
0
19
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
64
10
0
0
73
0
0
0
0
10
10
% K
% Leu:
0
0
0
0
0
0
0
0
10
0
73
10
0
0
0
% L
% Met:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
10
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
10
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
55
10
0
0
0
19
10
0
0
0
% R
% Ser:
10
10
0
19
10
0
10
0
0
19
0
0
10
0
0
% S
% Thr:
0
0
19
0
0
0
64
64
0
0
0
0
10
0
0
% T
% Val:
0
10
64
10
0
10
0
0
0
0
0
10
0
0
64
% V
% Trp:
0
0
0
0
0
0
0
0
10
10
10
0
0
0
0
% W
% Tyr:
73
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _